UBIQUITINATION IN THE REGULATION OF AUTOPHAGY

Ubiquitination in the regulation of autophagy

Autophagy, an efficient and effective approach fit shaced shirt to clear rapidly damaged organelles, macromolecules, and other harmful cellular components, enables the recycling of nutrient materials and supply of nutrients to maintain cellular homeostasis.Ubiquitination plays an important regulatory role in autophagy.This paper summarizes the most

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Hedgehog pathway inhibitors for locally advanced and metastatic basal cell carcinoma: A real-world single-center retrospective review.

Basal cell carcinoma (BCC) is highly curable by surgical excision or radiation.In rare cases, BCC can be locally destructive or difficult to surgically remove.Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50-60% response rate.Long-term toxicity includes muscle spasms and weight loss leading to dose decreases.This retrospective ch

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